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General Chemistry

Conjugate

Definition and meaning of Conjugate in chemistry.

Conjugate describes either species in a conjugate acid-base pair: two chemical species that differ from each other by exactly one proton (H+), as defined by the Brønsted-Lowry theory of acids and bases.

In more detail

When a Brønsted-Lowry acid donates a proton, it becomes its conjugate base; when a base accepts a proton, it becomes its conjugate acid. Every acid-base reaction produces a new conjugate pair, and the strength of an acid or base is inversely related to the strength of its conjugate (a strong acid has a very weak conjugate base, and vice versa). This relationship underlies buffer chemistry, since a buffer solution relies on a weak acid and its conjugate base (or a weak base and its conjugate acid) coexisting to resist pH change.

Key facts

FieldGeneral Chemistry
Defined byBrønsted-Lowry acid-base theory
RelationshipConjugate pair differs by one H+
Common pairNH4+ / NH3
Example

When acetic acid (CH3COOH) donates a proton to water, it forms its conjugate base, the acetate ion (CH3COO-), while water accepts the proton to become its conjugate acid, the hydronium ion (H3O+).

Frequently asked questions

How do you find the conjugate base of an acid?

Remove one H+ (and reduce the overall charge by one) from the acid's formula. For example, removing H+ from HCl gives its conjugate base, Cl-.

Can a species act as both a conjugate acid and a conjugate base?

Yes; amphiprotic species like HCO3- or H2O can act as either, since they can both donate and accept a proton depending on the reaction partner.

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