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General Chemistry

Conjugate Acid-Base Pair

Definition and meaning of Conjugate Acid-Base Pair in chemistry.

A conjugate acid-base pair is a set of two chemical species that differ from each other by exactly one proton (H⁺): the acid, which donates the proton, and its conjugate base, which is what remains after the proton is lost.

In more detail

This concept comes from the Brønsted-Lowry theory of acids and bases, in which acid-base reactions are proton-transfer reactions. Every such reaction involves two conjugate pairs: the acid transfers a proton to a base, generating the conjugate base of the first species and the conjugate acid of the second. There is an inverse relationship in strength within a pair, a strong acid has a weak conjugate base, and a weak acid has a relatively stronger conjugate base, which underlies buffer behavior and equilibrium calculations.

Key facts

FieldGeneral Chemistry
General formHA (acid) / A⁻ (conjugate base)
Defining featureDiffer by exactly one H⁺
Strength trendStronger acid ⇒ weaker conjugate base
Example

Acetic acid (CH3COOH) and the acetate ion (CH3COO⁻) are a conjugate acid-base pair: CH3COOH donates a proton to water, becoming CH3COO⁻, while water accepts the proton to become its conjugate acid, H3O⁺.

Frequently asked questions

How do you spot a conjugate acid-base pair in a reaction?

Find two species on opposite sides of the equation that differ by only one H⁺; the species with the extra proton is the acid, and the one without it is its conjugate base.

What is the conjugate base of water?

The hydroxide ion, OH⁻, formed when water donates one proton.

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