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Analytical Chemistry

Nujol

Definition and meaning of Nujol in chemistry.

Nujol is a viscous mineral oil composed of saturated hydrocarbons, used in analytical chemistry to prepare samples for infrared spectroscopy and X-ray crystallography.

In more detail

In infrared spectroscopy, Nujol is ground with a solid sample to form a 'Nujol mull,' creating a uniform paste for analysis; its characteristic C-H absorption bands (around 2850-2960 cm⁻¹, with additional bending bands near 1460 and 1375 cm⁻¹) must be accounted for during data interpretation. In X-ray crystallography, Nujol serves as an inert mounting medium for crystals because it is largely transparent to X-rays and produces minimal background scattering. Its chemical inertness and low volatility make it ideal for both applications.

Key facts

Chemical CompositionMixture of saturated hydrocarbons (alkanes) of higher molecular weight than kerosene, typically C18 and higher
Primary ApplicationInfrared spectroscopy sample preparation (Nujol mull)
Secondary ApplicationX-ray crystallography crystal mounting
FieldAnalytical Chemistry
Example

A chemist preparing an unknown solid compound for infrared spectroscopy might grind it with Nujol using a mortar and pestle to form a thick paste (Nujol mull), then place it between two sodium chloride plates for measurement.

Frequently asked questions

Does Nujol interfere with IR spectra?

Yes, Nujol exhibits strong C-H stretching absorption bands around 2850-2960 cm⁻¹ (plus bending bands near 1460 and 1375 cm⁻¹) that appear in spectra, but these regions are well-characterized and easily identified, allowing analysts to distinguish them from sample peaks during interpretation.

Why is Nujol preferred for X-ray crystallography over other mounting media?

Nujol is largely transparent to X-rays and produces minimal background scattering, so it does not interfere with or obscure the crystal diffraction pattern being measured.